Phyto-oestrogens and the great soya debate
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چکیده
who follow natural diets and a holistic lifestyle appear to escape menopausal symptoms. Japanese women, for example, rarely experience hot flushes and other associated menopausal complaints (Aldercreutz et al 1992, Beyene 1986). On balance and considering the health risks, natural alternatives may be the best and safest option towards management of patients. However, in some instances HRT supplementation is an unavoidable measure in the clinical management of menopause and has proven to be an invaluable treatment option for some women (see Table 1). Both oestrogen and progesterone are available in natural plant form. Plant sterols, such as those found in soybeans and yams, are the basis upon which many cheap, commercially available hormones are made. For many women, natural progesterone cream can control hot flushes without the use of oestrogen; the body is thought to synthesise oestrogen from it as needed (Walker and Brown 1998). Progesterone is a hormone precursor, from which other hormones are made in the body. Studies also show that natural progesterone can be as effective as their synthetic counterparts, progestins, in protecting against uterine cancer (Roan 1996). Natural oestrogen and progesterone creams derived from plants may also be administered (such as Estraderm and Estraderm V). Preliminary research suggests The endocrine pattern in peri-menopausal women is associated with declining ovarian function resulting in plummeting oestrogen concentrations and complete halting of progesterone production. Consequently, and via negative feedback response, the pituitary gland signals the adrenal to increase its hormone output, particularly oestrogen. When this standby system is fully operational, the menopause should occur with few or no side effects. The reason it fails for so many women in the West has been strongly attributed to adrenal exhaustion caused by stress, low blood sugar and poor diet (Walker and Brown 1998). Interestingly, women in other cultures Yaso Shan looks at the natural alternatives available for combating the unwanted side effects of the menopause
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Association between dietary phyto-oestrogens and bone density in men and postmenopausal women.
Phyto-oestrogens have been associated with a decreased risk for osteoporosis, but results from intervention and observational studies in Western countries have been inconsistent. In the present study, we investigated the association between habitual phyto-oestrogen intake and broadband ultrasound attenuation (BUA) of the calcanaeum as a marker of bone density. We collected 7 d records of diet, ...
متن کاملBioavailability of phyto-oestrogens.
The term phyto-oestrogen encompasses isoflavone compounds, such as genistein and daidzein, found predominantly in soya products and the lignans, such as matairesinol and secoisolariciresinol, found in many fruits, cereals and in flaxseed. There is evidence that they have potential health benefits in man particularly against hormone-dependent diseases such as breast and prostate cancers and oste...
متن کاملPns702 184..195
As oestrogen deficiency is the main cause in the pathogenesis of osteoporosis hormonereplacement therapy remains the mainstay for prevention. However, prophylaxis by hormonereplacement therapy is limited. Phyto-oestrogens, which are weakly-oestrogenic compounds present in plants, deserve particular mention because emerging data support the suggestion that they may prevent bone loss associated w...
متن کاملInfluence of ethnic origin (Asian v. Caucasian) and background diet on the bioavailability of dietary isoflavones.
Soya isoflavones: genistein and daidzein are increasingly consumed in Western countries. Their beneficial effects are discussed considering nutrition and health in Asia. The present study aimed to check whether chronic ingestions, ethnic origin and dietary context can influence soya phyto-oestrogen bioavailability. Two prospective trials were carried out to blindly assess the pharmacokinetics a...
متن کاملEstimated intake of dietary phyto-oestrogens in Australian women and evaluation of correlates of phyto-oestrogen intake
The role of dietary phyto-oestrogens in health has been of continued interest and debate, but data available on the distribution of intake in the Australian diet are scarce. Therefore, we aimed to estimate phyto-oestrogen consumption in Australian women, describe the pattern of intake and identify correlates of high phyto-oestrogen intake. Study participants were 2078 control women (18-79 years...
متن کاملXeno-oestrogens and phyto-oestrogens are alternative ligands for the androgen receptor.
The androgen receptor (AR) plays a critical role in prostate cancer development and progression. This study aimed to use a computerized docking approach to examine the interactions between the human AR and phyto-oestrogens (genistein, daidzein, and flavone) and xeno-oestrogens (bisphenol A, 4-nonylphenol, dichlorodiphenyl trichloroethane [DDT], diethylstilbestrol [DES]). The predicted three-dim...
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